Free to implement self-organised sessions, lunch and rooms provided
10.00 - 16.30 Self-organised session 1
Dosimetry in B fields workshop
Satellite symposium on
Standards and procedures for dosimetry and QA in MRgRT

Within the project “Metrology for MR guided radiotherapy” funded by the European Metrology Programme for Innovation and Research, standards and procedures for dosimetry and QA in Magnetic Resonance-guided radiotherapy (MRgRT) are being developed (mrgrt-metrology). Ongoing developments and preliminary results are presented at this dedicated one-day symposium. Researchers interested or working in this field are invited to participate and to discuss the current state of the art methods.

The day is divided in four blocks of the main “hot” topics in MR-guided-RT, which are covered by wonderful line-up of key-speakers. Don’t miss the opportunity to boost your MRgRT-dosimetry knowledge with this great overview.

Registration is open until the 31st of May. See below for further details. Updates on the program will be published on the website. Current draft of the program is as follows:

Reference dosimetry for MRgRT devices
Primary standards for kB - Leon de Prez (VSL, Netherlands)
Snap oral - Experimentally derived ion chamber magnetic field correction factors using a variable field on an in-line MR-linac -Jarrad Begg (South Western Sydney LHD, Australia)
kB from conventional linacs - Stefan Pojtinger (PTB, Germany)
kB using indirect methods – Alanine - Ilias Billas (NPL, United Kingdom)
kB using indirect methods – kbm/reading - Bram van Asselen (UMCU, Netherlands)
Fricke as secondary standard - Maria Trachsel (METAS, Switzerland)
Discussion: Towards a CoP for reference dosimetry - Jeroen vd Kamer (NKI-AVL, Netherlands)

Relative Dosimetry for MRgRT Treatment planning systems
Snap oral - The dose response of the PTW 60019 microDiamond in magnetic fields: Characterisation for the Australian MRI-linac -Natalia Roberts (UOW, Australia)
Snap oral - The effect of rotation and tilt on the response of the Exradin A28MR ionization chamber in a transverse magnetic field of 0.35T - Bhargesh Kandarp Shukla (DKFZ, Germany)
Snap oral - Spectral characterization of plastic scintillation detector response as a function of magnetic field strength - Eric Simiele (Univ of Wisconsin, USA)
Snap oral - Novel silicon dosimeters that measure dose in the build-up region and penumbra of an MRI-linac - Peter Metcalfe (UOW, Australia)
Water tank measurements and detectors for MRI-Linac - Simon Woodings (UMCU, Netherlands)
Radiation field characteristics in B-fields - Ralf-Peter Kapsch (PTB, Germany)

Monte Carlo simulations in magnetic fields
Monte Carlo in the pressence of magnetic fields - what's different - Hugo Bouchard (UdM, Canada)
Experimental benchmarking Monte Carlo based detector response simulations - David Shipley (NPL, United Kingdom)
Theoretical benchmarks for Monte Carlo based detector response simulations - Jacco de Pooter (VSL, Netherlands)
MC implementations for clinical purpose - Iwan Kawrakow (ViewRay, USA)

QA and workflow procedures for MRgRT
MRI QA - Marielle Philippens (UMCU, Netherlands)
Gel dosimetry - Christel Stien (CEA, France)
Snap oral - Heterogeneous and homogeneous 3D dosimeters for MR-IGRT systems - Hannah Lee (MDA, USA)
Film dosimetry - Daan Hofmans (VUMC, Netherlands)
Dosimetric effects of air cavities - Jane Shortall (Christie, United Kingdom)
Detectors for patient specific QA - Ian Hanson (RM, United Kingdom)
Antropomorphic phantoms To be determined (DKFZ, Germany)
Airborn electrons Sara Hackett (UMCU, Netherlands)

The satellite symposium is being held on June 30th, 2018 prior to the 6th MRinRT congress, between 10 am and 5 pm, at UMCU, Heidelberglaan 100, Utrecht.

To register please go to mrinrt-satelite-symposium. The deadline for registration is May 31. Advance registration for the meeting is required, but there is no fee.

For questions please contact:
Dr. Jacco de Pooter
Open for additional self-organised sessions
16.30 - 18.30 Welcome reception and tour through department

10.30 - 11.00Registration, welcome
11.00 - 12.15Keynote lectures
Chair: Lagendijk
o Prof. Debus - Where do we go with online and real-time MRI guidance?
o Prof Luijten - Developments in MRI
12.15 - 13.00Lunch
13.00 - 14.30proffered papers Clinical 1
Chair: Menard, Jingu
Clinical experience from MRI-only radiotherapy – pearls and pitfalls
A two-year clinical experience with MR-only planning for prostate
N. Tyagi
Assessment of inter- and intrafraction displacement of individual axillary lymph nodes on MRI
MR-guided high-dose-rate (HDR) brachytherapy or integrated volumetric arc therapy (VMAT) for intraprostatic dose escalation in localized prostate cancer
Focal treatment of locally recurrent prostate cancer with MRI-guided salvage high-dose-rate brachytherapy
van Son
Impact of repeated MR imaging for cervical cancer patients inside a combined brachy HDR and MRI treatment theatre
de Leeuw
Cine-MR based intra-fraction motion assessment for MR-Linac treatment of prostate cancer
de Muinck Keizer
Can pre brachytherapy MRI and deformable registration replace the MRI with applicator in place?
Comparison of metabolic abnormality extension from MR spectroscopy with clinical target volume in glioma patients
14.30 - 15.00Break
15.00 - 16.30proffered papers MRI guided Radiotherapy 1
Chair: Mutic, Low
How would you plan for precise dose-painting of involved lymph nodes?
Integrating a low-field open MR scanner with a static proton therapy research beamline: proof of concept.
Implementation of a 4D MRI workflow for abdominal radiotherapy treatment planning.
Gastrointestinal 4D MRI with respiratory motion correction.
Detection and characterisation of prostate cancer from multiparametric MRI using machine learning techniques for bio-focused radiotherapy.
Application of a deep convolutional neural network to segment the parotid glands on MR images.
MR-only brain radiotherapy: Feasibility of dose calculation on synthetic CTs generated by a CycleGAN trained with unpaired data.
Development of a method to assess on-set treatment 3D positional verification for MR-only pathways.
16.30 - 16.45 Break
16.45 - 18.30Industrial symposium gold sponsors
Chair: Raaymakers

o Viewray
Clinical Benefits of MR-Guided On-Table Adaptive Radiation Therapy on MRIdian Linac

Ben Slotman, MD PhD
VU University Medical Center
o Elekta
Driving the Transformation of Cancer Care

Ioannis Panagiotelis, PhD
Chief Marketing and Sales Officer

Clifton David Fuller, MD, PhD
Associate Professor, Department of Radiation Oncology
Associate Director of MR Programmatic Development
The University of Texas MD Anderson Cancer Center, Houston, TX, USA
o Philips
MRI in Radiation Therapy– between standardization and personalization
Dr. Gerald Schubert,
Clinical science manager MR Therapy,
18.30 - 21.00poster session and BBQ in garden at conference venue

09.00 - 10.00 Symposium Deep learning
Chair: Fuller, Greer
Deep learning in image processing for Radiology.
prof van Ginneken
Deep learning in image processing for Radioherapy.
asoc. Prof van den Berg
10.05 - 11.35proffered papers Clinical 2
Chair: Debus, Schultz
Treatment response prediction using texture features from longitudinal diffusion MRI in sarcoma patients,
Can conventional MRI predict survival in pediatric ependymoma patients?
Radiologic response on MRI and pathologic response after MR-guided single dose preoperative radiotherapy in breast cancer patients,
Prostate tumor prediction model for automated delineation QA on multiparametric MRI,
van Schie
Baseline dynamic R2* MRI in rectal cancer is associated with chemoradiotherapy outcome,
Roe Redalen
Clinical outcome after MRI guided (chemo-)radiotherapy for advanced cervical cancer; a single center experience,
Variability in Expert Delineation of Targets and Organs-at-Risk in Gliomas for CT-MRI and MRI-only workflows,
MR-based target definition for laryngeal cancer; The overall results of 8 years of research at the UMC Utrecht,
11.35 - 11.50Short coffee break
11.50 - 12.30Panel discussion MR in RT
Chair: Debus, Lagendijk
Members panel discussion: Slotman, Schulz, Fuller, Barton
Will the MRI linac systems replace conebeamCT systems as standard RT system?
Will all MRI guided treatments become hypofractionated?
12.30 - 13.30Lunch
13.30 - 15.00proffered papers QA 1
Chair: Liney, Li
Summary from the satellite symposium on Standards and procedures for dosimetry and QA in MRgRT, TBD
Geometric and dosimetric validation of 4D-MRI guided liver SBRT on the MR-linac.
van de Lindt
Dosimetric impact of MR geometric distortions – A study on head and neck cancers.
Longitudinal measurements of multiparamteric MRI: A phantom study.
Heterogeneous and homogeneous 3D dosimeters for MR-IGRT systems.
Surface dose measurements in an MR image-guided radiation therapy system using OSLDs: comparison with and without a static 0.35 T magnetic field.
Commissioning of a 4D dynamic MRI motion phantom on a 3T MR scanner: motion validation study.
Indication of accurate gold fiducial marker identification in a prostate MRI only radiotherapy workflow using C-Arm X-ray imaging.
15.00 - 15.30 Break
15.30 - 17.00proffered papers MRI
Chair: Thorwarth, Nyholm
Robust quantitative diffusion weighted MR on an MR-Linac system.
Ultra fast image reconstruction for real-time MRI-guided radiotherapy by removing undersampling artefacts using deep learning.
Feasibility of alternating repetition time balanced steady state free precession MRI on an MR-linac.
Optimizing acquisition speed and contrast of respiratory correlated 4D-MRI on the 1.5T Unity MRI-linac.
Imaging performance of a dedicated radiation transparent RF coil on a 1.0 Tesla inline MRI-Linac.
Accelerating 3D head-and-neck MR imaging using convolutional neural network for MR-guided radiotherapy.
Hybrid UTE/Dixon Acquisition for synthetic CT generation.
Multi-Resolution radial MRI to Reduce IDLE time in pre-beam imaging on an MR-Linac (MR-RIDDLE).
17.00 - 17.45debate
Chair: van der Heide, vd Voort v Zyp
• The future of local prostate cancer care is non- invasive radiotherapy:
o Against (pro-surgery): Henk vd Poel
o For (pro-radiotherapy): Peter Hoskin
17.45-18.15presentation by Bibian Mentel (Paralympic gold medallist) and young investigators awards ceremony
Chair: Raaymakers
19.00 - 00.00Conference dinner and party at Museum Speelklok, Steenweg 6, Utrecht

09.00 - 10.30proffered papers MRI guided Radiotherapy 2
Chair: Balter, Oelfke
Characterizing MRI-guided tracking using the Elekta 1.5T MRI-linac system.
Tumour trailing on the MR-Linac: a first experimental proof-of-principle demonstration.
Motion model and super-resolution reconstruction from multi-slice MR image data using an MR-derived surrogate.
Towards fast adaptive VMAT sequencing for the MRI-linac.
Integrating a low-field open MR scanner with a static proton therapy research beamline: Characterisation of in-beam imaging performance.
Towards real-time MR-guided high-dose-rate brachytherapy.
Tumor probability model for focal salvage strategies in recurrent prostate cancer patients after radiotherapy.
10.30 - 10.45short coffee break
10.45 - 12.15 proffered papers QA 2
Chair: de Pooter, Ibbott
Novel silicon dosimeters that measure dose in the build-up region and penumbra of an MRI-linac.
Error estimation of slice chipping effects due to gradient non-linearity on the MR-Linac.
Dosimetric verification of Monte Carlo simulated effects of air cavities during MR guided Radiotherapy using EBT3 GafChromic film.
Spiraling contaminant electrons increase doses to surfaces outside the photon beam of an MRI-linac with transverse magnetic field.
Experimentally derived ion chamber magnetic field correction factors using a variable field on an in-line MR-linac.
Direct calorimetric measurement of ion chamber magnetic field correction factors, kB, in a 1.5 T B-field of an MRI-linac.
de Prez
Reference dosimetry in MRI-linac using alanine detector.
12.15-12.30Proposals and voting next meeting and adjourn
Chair: Lagendijk

QA1Uncertainties in the accumulation of local physical and biological dose from daily patient imaging.
Nina Niebuhr
QA2Polymer gel-based measurements of radiation isocenter accuracy in magnetic fields.
Stefan Dorsch
QA3Verification and commissioning of a magnetic resonance image guided linear accelerator’s Monte Carlo dose calculation algorithm within a heterogeneous phantom.
Alex Price
QA4Characterising the temporal stability of full field of view MRI geometric distortions on multiple scanners.
Emily Johnstone
QA5Absorbed dose calculation based on CBCT data for head and neck cancer patients.
Emilia Palmér
QA6Spectral characterization of plastic scintillation detector response as a function of magnetic field strength.
Eric Simiele
QA7Forward Peaked Finite Element Angular Discretization towards a Fast Deterministic Dose Calculation for MRI-guided Radiotherapy.
Ray Yang
QA8Magnetic field effects on beam output from a 1.5 T pre-clinical MR-linac.
Hannah J. Lee
QA9MR-guided needle implant device for HDR brachytherapy: in air and phantom measurements of spatial accuracy.
Marinus Moerland
QA10Experimental determination of the intra-type variation of ionization chamber’s response in magnetic fields.
Stefan Pojtinger
QA11Simplified CT images for dose calculation for pelvic tumour patients.
Josefine Handrack
QA12An assessment of MRI reproducibility for the purpose of radiotherapy treatment planning.
Lois, Holloway
QA13QuantMRI: An automated imaging pipeline for the management of MR data.
Teo Stanescu
QA14Reference dosimetry in the presence of a magnetic field: a novel formalism.
Bram van Asselen
QA15Characterisation of MR Spatial Distortion of the Elekta MR-Linac.
Chick, Joan
QA16Cone beam CT as a clinical QA tool for prostate MRI-only workflows.
Emilia Persson
QA17The assessment of polymer gel for 3D dosimetry in magnetic resonance-image guided radiotherapy.
Yvonne Roed
QA18Characterisation of the Starcheck maxi MR ionization chamber array in an inline magnetic field.
Urszula Jelen
QA19The dose response of the PTW 60019 microDiamond in magnetic fields: Characterisation for the Australian MRI-linac.
Natalia Roberts
QA20Evaluating the Octavius 4D MR System.
Edmund Goodwin
QA21The effect of rotation and tilt on the response of the Exradin A28MR ionization chamber in a transverse magnetic field of 0.35T.
Bhargesh Kandarp Shukla
C1Diffusion-weighted magnetic resonance imaging during brachytherapy of locally advanced cervical cancer: preliminary results.
Chiara Tenconi
C2Evaluation of bulk-density pseudo-CT for MR-only treatment planning of MRI-guided accelerated partial breast irradiation.
Maureen Groot Koerkamp
C3Radiologist led training and its effect on inter-observer variation in OAR and GTV delineation in MRI of lung cancer patients.
Sean Brown
C4 MR, CT and Cone-Beam CT for metastatic lymph node visualisation in lung cancer patients.
Michael Dubec
C5MRI-based urethra assessment and delineation for MR-only external beam treatment planning.
Neelam Tyagi
C6A comparison of cone beam CT and different MR sequences for use in image guided radiotherapy for cervical cancer.
Anthea Cree
C7Longitudinal effects of radiation therapy on white matter structures, as measured by diffusion MRI.
Victor Andrei Bodiut
C8Motion variability in 4D lung treatments for PBS proton therapy using 4DCT(MRI).
Miriam Krieger
C9Understanding the Canadian landscape to guide practice change: MRI in radiation therapy.
Mikki Campbell
C10Advanced Radiotherapy Technologies Network In The UK (ART-NET) - A focus on lung cancer.
Brown, Sean
C11Changes in MRI-derived Prostate Cancer Diffusion Parameters during and after Hypofractionated SBRT.
Kristen Zakian
C12Repeatability of T2 and ADC mapping on the MR-Linac in prostate cancer patients.
Ernst Kooreman.
C13Lung tumor delineation and motion assessment using T2w respiratory-correlated 4DMRI.
Guang Li
C14Interobserver GTV delineation variation on MRI versus PET-CT in oesophageal cancer.
Sophie Vollenbrock
C15MRI guided radiotherapy of centrally located thoracic tumors: effect of cardiac motion.
Yingli Yang
C16Target volume delineation of laryngeal cancer using diffusion-weighted MRI validated by pathology: a case series.
Hans Ligtenberg
C17A systematic review of organ motion management techniques for CT/MRI simulation for lung and abdominal radiotherapy.
Richard Speight
C18Automatic Contour Propagation of Organs-at-Risk on Serial MRIs and Dosimetric Implications in Glioblastoma Patients Undergoing Chemo-Radiation.
Chia-Lin Tseng
C19Case Study – Utility of cardiac MRI mapping in the quantification of myocardial toxicity following concurrent chemoradiation for oesophageal Carcinoma.
Simon Tang
C20Experiences of MR simulation as an enabler for Liver SABR.
Richard Speight
C21Morphological analyses of post-treatment changes in cortical thickness in a brain tumour patient.
Steven Nagtegaal
C22Multiparametric magnetic resonance imaging for the detection and localisation of prostate cancer.
Neda Gholizadeh
C23Investigating the impact of training on delineation variability with two MR sequences for prostate radiotherapy.
Jonathan Wyatt
MR1Lung tumor delineation and motion assessment using T2w respiratory-correlated 4DMRI.
Guang Li
MR2Image quality enhancement of super-resolution time-resolved 4DMRI by two-step hybrid deformable image registration.
Guang Li
MR3Implementation of a software framework for automated offline MR image reconstructions.
Tim Schakel
MR4Production of Beam’s Eye View MR images for RT-MRI hybrids via specially-designed gradient hardware.
Keith Wachowicz
MR5feasibility of BLADE-DWI for head and neck radiation treatment planning: phantom and volunteer studies.
Yao, Ding
MR6A custom-designed flexible MR coil for spine radiotherapy treatment planning.
Neelam Tyagi
MR7Coil-replacement shimming reduce inhomogeneity-induced artifacts in sodium imaging.
Fróði Gregersen
MR8Assessment of pelvic imaging for a static inline MRI-Linac.
Jarryd, Buckley
MR9Minimal processing pipeline of diffusion MRI data in brain cancer patients.
Szabolcs David
MR104D-T2w MRI on an MR-linac.
Joshua Freedman
MR11Zero TE based pseudo CT conversion for Head and Neck: from feasibility to a Radiation Therapy workflow-friendly solution.
Cristina Cozzini
MR12Radiologically Transparent RF Coils for Parallel-field Linac-MR.
Radim, Bart
MR13MR-based pseudo CT conversion for Radiation therapy planning in pelvis using sero TE and lava flex.
MgRT1Evaluation of novel method for automatic generation of synthetic-CT images.
Brige, Chugh
MgRT2Evaluation of surrogate signals derived from MR images to build respiratory motion models.
Elena Tran
MgRT3Experimental validation of magnetic field deflections of proton beams for online MR-guided PT.
Gabriel, Marmitt
MgRT4Non-rigid CT to MR registration for online external beam radiotherapy guidance.
Cornel Zachiu
MgRT5Towards Real-Time PBS dose accumulation observation using dynamic MRI.
Damien Dasnoy
MgRT6 R-IDEAL 0 simulation study: Investigation of the potential dosimetric benefits of treating lymph node oligometastases on the 1.5T MR-linac.
Dennis, Winkel
MgRT74DMRI-based 4D dose calculation for MR-guided proton therapy of pancreatic cancer.
Kai Dolde
MgRT8Assessment of the stability of radiomic features in rectal cancer using test-retest MRI.
Robba Rai
MgRT9MRI-only based radiation therapy - HIP prostheses are not an exclusion criterion for prostate cancer patients using MRI-only radiotherapy.
Lauri, Koivula
MgRT10Dose escalation in head and neck cancer using high-field MRI-linac techniques.
Marcel, Nachbar
MgRT11Feasibility of MRI-only photon and proton dose calculations for abdominal pediatric patients.
Filipa Guerreiro
MgRT12Dosimetric commissioning of the Australian MRI-Linac.
Urszula Jelen
MgRT13Multimodality assessment of gold fiducial marker inter-distance measurements for prostate patients in an MRI-only based radiotherapy workflow.
Christian Gustafsson
MgRT14Quantifying the dosimetric effects of arm position and structure-avoidance for liver SBRT on the MR-linac.
Wouter van den Wollenberg
MgRT15Feasibility of fast synthetic CT generation with deep learning for MR-guided Radiotherapy of prostate cancer patients.
Matteo Maspero
MgRT16Effects of time-varying magnetic fields from the MRI’s gradient coils on a proton beam.
Dan Michael Santos
MgRT17Evaluation of MR-guided motion management on a prototype inline MRI-Linac.
Bin Dong
MgRT18Feasibility of whole brain voxelwise statistical analysis of longitudinal diffusion tensor imaging of single subject: quantitative comparisons of three non-parametric, data-driven methods.
Tong Zhu
MgRT19Dosimetric feasibility of on-body receive array placement to enhance image quality in the MR-linac.
Stefan Zijlema
MgRT20Expanding the horizon of MriPlanner to new anatomical regions; the female pelvis.
Rickard Cronholm
MgRT21The impact of 2D cine MR imaging parameters on automated localization of abdominal organs.
Martin Menten
MgRT22Detecting abrupt patient motion using the noise navigator on an MR-linac system.
Robin Navest
MgRT23Online prostate plan adaptation for simulated volume changes on the 1.5T MR-Linac.
Robert Chuter
MgRT24Head and Neck Synthetic MR Only protocol (HAN-SOLO).
Laura O'Connor
MgRT25Multi-Fractional Planning Study for Lung Cancer Treatment: Impact of Magnetic Fields and Treatment Procedures.
Oliver, Schrenk
MgRT26Bulk-density assignment recommendations for MR-linac adaptive planning.
Alex Dunlop
MgRT27Theragnostic imaging using DW-MRI and isotoxic dose escalation for muscle-invasive bladder cancer.
Jane Rogers